Related topics: protein · messenger rna

Researchers discover how hibernating ribosomes wake up

In research published in Proceedings of the National Academy of Sciences (PNAS), Mee-Ngan F. Yap, Ph.D., assistant professor of biochemistry and molecular biology at Saint Louis University, has uncovered the way a bacterial ...

New protein regulated by cellular starvation

Researchers at the Center of Genomic Integrity, within the Institute for Basic Science (IBS), have found out an unexpected role for a protein involved in the DNA repair mechanism. The protein SHPRH not only helps to fix mistakes ...

Translating the ribosome's grim role

A large number of long noncoding RNAs (lncRNA) have been found associating with the ribosome, the protein-making machinery in the cytoplasm. What the so-called 'noncoding' RNAs are doing on the ribosome, whose main job is ...

New drug strategy: Target ribosome to halt protein production

The discovery of a chemical compound that halts the production of a small set of proteins while leaving general protein production untouched suggests a new drug search strategy: Find compounds that target undesired proteins ...

Protein chaperone takes its job seriously

For proteins, this would be the equivalent of the red-carpet treatment: each protein belonging to the complex machinery of ribosomes—components of the cell that produce proteins—has its own chaperone to guide it to the ...

Quality control inside the cell

The ability to dispose of proteins that are either aberrant or (in the worst case) toxic is fundamental to a cell's survival. Researchers from Charité - Universitätsmedizin Berlin have been able to demonstrate the manner ...

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