Related topics: protein · messenger rna

Secrets of a little-known cancer ally revealed

Human cancers often have a little recognized ally— the increased size and number of a cell's organelles called the nucleolus. The nucleolus is where ribosomes, the cellular protein factories, are made. Ribosomes can also ...

Linking cytosolic and chloroplast ribosome biogenesis in plants

Scientists at Tokyo Institute of Technology (Tokyo Tech) have found that eukaryotic and bacterial growth regulation systems of independent origins are connected to the control of chloroplast rRNA transcription in a primitive ...

Ribosomes found to induce somatic cell pluripotency

In 2012, a Japanese research group discovered that human skin cells acquire pluripotency when introduced to lactic acid bacteria (Lactobacillus acidophilus). Now, the same group of researchers has found that the cause of ...

Scientists discover a molecular timer based on stalling ribosomes

A molecular biologist from Lomonosov Moscow State University and international colleagues discovered a special mechanism of protein synthesis regulation that they called a "molecular timer." It controls the number of protein ...

Finding form by folding

Ribosomes are the organelles responsible for protein synthesis in cells. LMU researchers have now dissected early steps in their assembly and visualized how their RNA components fold correctly and find their places in the ...

Teaching antibiotics to be more effective killers

Research from the University of Illinois at Chicago suggests bond duration, not bond tightness, may be the most important differentiator between antibiotics that kill bacteria and antibiotics that only stop bacterial growth.

How ribosomes shape the proteome

Cells are crowded with macromolecules, which limits the diffusion of proteins, especially in prokaryotic cells without active transport in the cytoplasm. While investigating the relationship between crowding, ionic strength ...

Discovery of a potential therapeutic target to combat trypanosomes

Yaser Hashem's team at the Laboratoire Architecture et Réactivité de l'ARN at CNRS's has discovered a new potential therapeutic target - located in the ribosome - to combat trypanosomes parasites. Using cryo-electron microscopy, ...

Hibernating ribosomes help bacteria survive

In the second of two high-profile articles published in recent weeks, Saint Louis University scientist Mee-Ngan F. Yap, Ph.D., in collaboration with the laboratories of 2009 Nobel laureate in chemistry Ada Yonath at the Weizmann ...

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