Evolutionarily conserved transport proteins, such as those belonging to the multidrug and toxic compound extrusion (MATE) superfamily, protect cells against toxic chemicals and contribute to multidrug resistance in cancer ...
Biochemistry
Jul 20, 2018
0
4
Antimicrobial resistant pathogens crowdsource friendly bacteria to survive in immune cells and cause disease, a new study by the University of Sheffield has revealed.
Cell & Microbiology
Jul 16, 2018
0
26
MSU-based biologists have reported new understanding of fungal drug resistance mechanisms. To study them, the scientists used baker's yeast expressing fluorescent proteins fused with the membrane transporters. Fungi activate ...
Cell & Microbiology
Jul 11, 2018
0
7
With antibiotic resistance spreading worldwide, there is a strong need for new technologies to study bacteria. EMBL researchers have adapted an existing technique to study the melting behaviour of proteins so that it can ...
Cell & Microbiology
Jul 6, 2018
0
12
Unlike other organisms, bacteria can take up genetic material from their environment. This ability to exchange genes enables them to pick up new traits such as different metabolic pathways, virulence genes and antibiotic ...
Cell & Microbiology
Jul 3, 2018
0
18
About half of all drugs, ranging from morphine to penicillin, come from compounds that are from—or have been derived from—nature. This includes many cancer drugs, which are toxic enough to kill cancer cells.
Biochemistry
Jun 21, 2018
0
5
Beta-lactam antibiotics, including penicillin, are one of the most widely used classes of antibiotics in the world. Though they've been in use since the 1940s, scientists still don't fully understand what happens when this ...
Biochemistry
Apr 9, 2018
0
109
Prostate cancer is the second most common cancer in men and the fifth leading cause of death from cancer in men worldwide, according to 2012 numbers. While several viable treatment options for prostate cancer exist, many ...
Biochemistry
Apr 2, 2018
0
115
Small populations of pathogenic bacteria may be harder to kill off than larger populations because they respond differently to antibiotics, a new study by Emory University finds.
Cell & Microbiology
Mar 13, 2018
0
169
Overcoming the natural resistance of plant cell walls to deconstruction, known as recalcitrance, is a major bottleneck to cost-effective biofuel production. In response, scientists modified lignin. Lignin is one of the polymers ...
Environment
Mar 1, 2018
0
22
