Piloting ribosomes past proline pairs

Certain proteins are known to require Translation Factor EF-P for their synthesis, and a new study enlarges the size of the set. As some of its members are involved in bacterial pathogenicity, the results are also of therapeutic ...

Watching the production of new proteins in live cells

Researchers at Columbia University, in collaboration with biologists in Baylor College of Medicine, have made a significant step in understanding and imaging protein synthesis, pinpointing exactly where and when cells produce ...

Study offers insight into the origin of the genetic code

An analysis of enzymes that load amino acids onto transfer RNAs—an operation at the heart of protein translation—offers new insights into the evolutionary origins of the modern genetic code, researchers report. Their ...

Preventing the spread of repression

Scientists at the Friedrich Miescher Institute for Biomedical Research have identified a novel and unexpected regulatory activity of RNA at the edge of inactive chromosomal regions. In their publication in Nature Structural ...

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