Scientists at Wageningen University have developed a new technique that opens new possibilities for research into novel drugs and tastier, healthier food. The new approach is called 'receptomics' and was published in the ...
Analytical Chemistry
Mar 5, 2018
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14
Scientists at Heptares Therapeutics have published the first high-resolution X-ray crystal structure of the complement C5a receptor (a G protein-coupled receptor, GPCR) binding a small molecule allosteric antagonist.
Biochemistry
Jan 4, 2018
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7
Danish researchers have just presented a previously unknown mechanism that inhibits the ability of cells to develop into cancer cells. Their findings have important implications for the understanding of how cancer starts, ...
Cell & Microbiology
Dec 15, 2017
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12
From a drug perspective, G protein-coupled receptors are the most utilised cell receptors in the body. They are uniquely accessible at the cell surface, and a third of all drugs sold in the US target them.
Biochemistry
Oct 31, 2017
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3
G protein-coupled receptors are the key target of a large number of drugs. Würzburg scientists have now been able to show more precisely how these receptors act in the cell interior.
Biochemistry
Sep 5, 2017
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7
Nematodes are a huge threat to agriculture since they parasitize important crops such as wheat, soybean, and banana; but plants can defend themselves. Researchers at Bonn University, together with collaborators from the Sainsbury ...
Biotechnology
Apr 13, 2017
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3
An international team including researchers from MIPT's Laboratory for Advanced Studies of Membrane Proteins have proposed an explanation of how bacteria process external signals. By identifying the detailed structure of ...
Cell & Microbiology
Apr 10, 2017
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196
A team of the Institute of Neurosciences of the University of Barcelona has participated in the design of the first large-scale interaction map of G-protein-coupled receptors in humans, the largest group of membrane proteins ...
Cell & Microbiology
Mar 16, 2017
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9
Researchers at Lund University in Sweden have taken an important step on the road to understanding the underlying mechanism of how and why animals can feel pain in connection with cold or heat. However, according to the study, ...
Biochemistry
Feb 9, 2017
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9
Insects, like mammals including humans, sort chemicals by taste into a few categories and use this information to decide whether to ingest or reject food.
Cell & Microbiology
Jan 23, 2017
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4
