How roots grow hair

The roots of plants can do a lot of things: They grow in length to reach water, they can bend to circumvent stones, and they form fine root hairs enabling them to absorb more nutrients from the soil. A team of researchers ...

The arrestin-GPCR connection

G-protein coupled receptors (GPCRs) are the "inbox" of environmental messages in mammalian cells. Because of their central role in signaling pathways, mutations resulting in abnormal GPCR functions cause a wide variety of ...

Helping to transport proteins inside the cell

Researchers at the University of Freiburg report a mechanism inside cells that transports proteins to the mitochondria. Their research has now been published in the science journal Cell Reports.

How microvilli form

The gut is lined by cells containing brush borders, which are composed of arrays of microvillar protrusions that help in nutrient absorption and provide a barrier against pathogens and toxins. Microbes such as E. coli can ...

Drug makes rats less likely to imbibe alcohol

Alcohol use disorders can have devastating effects on a person's health, relationships and finances. Yet for some, the feeling they get when taking a drink temporarily outweighs these other concerns. Now, researchers have ...

Computer simulation of receptors reveals a new ligand-binding site

Using a computer simulation of an important receptor, EPFL scientists have discovered a novel binding site for natural ligands and drugs. The new site might be present on other receptors and can be exploited in novel treatments ...

Beef peptides block bitter tastes

From burgers to steaks, beef has a long history of being a delicious part of dinner. But what if that pleasant experience of eating beef could extend beyond the dinner plate? Now, one group reports in ACS' Journal of Agricultural ...

Understanding a cell's 'doorbell'

A multi-institutional project to understand one of the major targets of human drug design has produced new insights into how structural communication works in a cell component called a G protein-coupled receptor (GPCRs), ...

Protein analysis enables precise drug targeting

Researchers from MIPT and several U.S. and Chinese universities have solved the structure of one of the most important nervous system proteins in complex with a number of drug molecules. The discovery opens up opportunities ...

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