In a study published in Proceedings of the National Academy of Sciences, Umeå researchers describe a natural product-like molecule, Tantalosin, that inhibits interaction between two proteins in complexes that reshape membranes ...
Biochemistry
May 3, 2024
0
27
For most human proteins, there are no small molecules known to bind them chemically (so-called "ligands"). Ligands frequently represent important starting points for drug development but this knowledge gap critically hampers ...
Biochemistry
Apr 25, 2024
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53
A new computer process developed by chemists at ETH Zurich makes it possible to generate active pharmaceutical ingredients quickly and easily based on a protein's three-dimensional surface. The new process, detailed in Nature ...
Biochemistry
Apr 24, 2024
1
37
Despite huge advances in our understanding of COVID-19 over the past four years, the disease is still very much among us—and there remains a lot to learn.
Cell & Microbiology
Apr 24, 2024
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28
Researchers at Weill Cornell Medicine have developed a powerful, new technique to generate "movies" of changing protein structures and speeds of up to 50 frames per second.
Molecular & Computational biology
Apr 17, 2024
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33
A recent UCLA study demonstrates a new process for screening T cells, part of the body's natural defenses, for characteristics vital to the success of cell-based treatments. The method filters T cells based on the receptor ...
Bio & Medicine
Apr 15, 2024
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46
Researchers have discovered ways to convert inhibitor-style targeted cancer drugs into small molecules known as degraders, which help destroy cancer-promoting proteins in cells.
Biochemistry
Apr 11, 2024
0
35
Researchers from The Australian National University (ANU) have made a discovery about a little understood protein in the human body that could help treat diseases that cause seizures, including epilepsy. The study is published ...
Cell & Microbiology
Apr 4, 2024
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3
One of the most striking features of human genes is that genetic information required to produce proteins is stored in a discontinuous form, wherein the coding information (exons) is punctuated with non-coding segments known ...
Molecular & Computational biology
Apr 4, 2024
0
10
In the battle against cancer and other diseases, scientists are developing molecular weapons that can be used to stop uncontrollable cell growth.
Biochemistry
Apr 3, 2024
0
1
