A new study shows that it is possible to use an imaging technique called cryo-electron microscopy (cryo-EM) to view, in atomic detail, the binding of a potential small molecule drug to a key protein in cancer cells. The cryo-EM ...
Biochemistry
Jan 29, 2016
0
20
Tracking the path of chemotherapy drugs in real time and at a cellular level could revolutionize cancer care and help doctors sort out why two patients might respond differently to the same treatment.
Bio & Medicine
Jan 14, 2016
0
637
Researchers at the University of Waterloo have discovered a new way to create designer proteins that have the potential to transform biotechnology and personalized medicines.
Biotechnology
Nov 24, 2015
0
29
Purdue researchers have devised a way to capture the finer details of complex cell processes by using tiny synthetic particles known as dendrimers, a technology that could lead to more targeted treatment for cancer.
Bio & Medicine
Nov 11, 2015
1
34
(Phys.org)—A team of researchers at MIT has found a way to modify proteins using palladium reagents, allowing for the possible creation of a host of therapeutic drugs. In their paper published in the journal Nature, the ...
Most pharmaceutical drugs consist of tiny molecules, which target a class of proteins found on the surfaces of cell membranes. Studying these subtle interactions is essential for the design of effective drugs, but the task ...
Biochemistry
Oct 23, 2015
0
920
Many of the drugs we take today to treat pain, fight cancer or thwart disease were originally identified in plants, some of which are endangered or hard to grow. In many cases, those plants are still the primary source of ...
Biochemistry
Sep 10, 2015
2
4633
The first three-dimensional image capturing a critical malaria 'conductor' protein could lead to the development of a new class of antimalarial drugs.
Cell & Microbiology
Jul 27, 2015
0
34
A new study led by University of Kentucky researchers suggests a new approach to develop highly-potent drugs which could overcome current shortcomings of low drug efficacy and multi-drug resistance in the treatment of cancer ...
Bio & Medicine
Jul 7, 2015
0
27
Scientists have pioneered the use of a high-powered imaging technique to picture in exquisite detail one of the central proteins of life – a cellular recycling unit with a role in many diseases.
Biochemistry
Jul 2, 2015
0
1479
