Protein drugs, which derive from biological sources, represent some of the most important and effective biopharmaceuticals on the market. Some, like insulin, have been used for decades, while many more based on cloned genes ...
Biochemistry
Sep 23, 2016
3
32
It probably isn't surprising to read that pharmaceutical drugs don't always do what they're supposed to. Adverse side effects are a well-known phenomenon and something many of us will have experienced when taking medicines.
Biochemistry
Aug 25, 2016
0
8
By identifying new compounds that selectively block mitochondrial respiration in pathogenic fungi, Whitehead Institute scientists have identified a potential antifungal mechanism that could enable combination therapy with ...
Diseases, Conditions, Syndromes
Aug 11, 2016
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6
Researchers have revealed the molecular structure of a protein produced by the Zika virus that is thought to be involved in the virus's reproduction and its interaction with a host's immune system.
Cell & Microbiology
Jul 25, 2016
1
160
Scientists have described an improved, cost-efficient method to isolate membrane proteins, a class of proteins that are the targets of more than 60 percent of approved therapeutic drugs.
Cell & Microbiology
Jul 25, 2016
0
5
Scientists using a technology called cryo-EM (cryo-electron microscopy) have broken through a technological barrier in visualizing proteins with an approach that may have an impact on drug discovery and development. They ...
Biochemistry
May 26, 2016
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191
Researchers have developed a light-activated tool to show how drugs need to be adapted to combat type 2 diabetes.
Biochemistry
Apr 11, 2016
1
30
If you suffer from atrial fibrillation (AF)—a condition where disorganized electrical signals cause the heart's upper chambers to contract quickly and irregularly—your doctor may prescribe an antiarrhythmic drug. While ...
Cell & Microbiology
Feb 29, 2016
0
11
Natural selection results in protein sequences that are only soluble to the level that is required to carry out its physiological function. However, in biotechnological applications, we need these proteins to survive concentrations ...
Cell & Microbiology
Feb 29, 2016
0
7
Researchers from Carnegie Mellon University (CMU) have created the first robotically driven experimentation system to determine the effects of a large number of drugs on many proteins, reducing the number of necessary experiments ...
Cell & Microbiology
Feb 9, 2016
0
13
