Proteins have now been designed in the lab to zip together in much the same way that DNA molecules zip up to form a double helix. The technique, whose development was led by University of Washington School of Medicine scientists, ...
Biochemistry
Dec 19, 2018
0
108
For the first time, scientists have created, from scratch, self-assembling protein filaments.
Biochemistry
Nov 8, 2018
1
56
Biologists at UC San Diego have succeeded in genetically engineering algae to produce a complex and expensive human therapeutic drug used to treat cancer.
Cell & Microbiology
Dec 10, 2012
1
0
Transmembrane β-barrel pores (TMBs) are extensively used for single-molecule DNA and RNA sequencing. They enable the miniaturization of a wide array of sensing and sequencing applications into portable USB-size devices and ...
Bio & Medicine
Jul 18, 2024
0
103
Many drug and antibody discovery pathways focus on intricately folded cell membrane proteins: when molecules of a drug candidate bind to these proteins, like a key going into a lock, they trigger chemical cascades that alter ...
Biotechnology
Jun 21, 2024
0
39
Multicellular organisms, like animals and plants, have complex cells with diverse functions. This complexity arises from the need for cells to produce distinct proteins that interact with each other. This interaction is crucial ...
Biochemistry
May 23, 2024
0
66
Many important medicines, such as antibiotics and anticancer drugs, are derived from natural products of bacteria. The enzyme complexes that produce these active ingredients have a modular design that makes them ideal tools ...
Cell & Microbiology
Mar 21, 2024
0
51
In the wake of the COVID-19 pandemic, scientists have been racing to develop effective treatments and preventatives against the virus. A recent scientific breakthrough has emerged from the work of researchers aiming to combat ...
Biotechnology
Mar 14, 2024
0
157
David Baker's group at the University of Washington, Seattle, U.S., have developed a novel deep learning method, RoseTTAFold All-Atom (RFAA), for prediction and design of complexes of proteins, small molecules, and nucleic ...
Biotechnology
Mar 11, 2024
0
1
Researchers at the University of Toronto have used an artificial intelligence framework to redesign a crucial protein involved in the delivery of gene therapy.
Biotechnology
Jan 29, 2024
0
116
