Scientists have successfully applied reinforcement learning to a challenge in molecular biology. The team of researchers developed powerful new protein design software adapted from a strategy proven adept at board games like ...
Biotechnology
Apr 20, 2023
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37
Most life on Earth is based on polymers of 20 amino acids that have evolved into hundreds of thousands of different, highly specialized proteins. They catalyze reactions, form backbone and muscle and even generate movement.
Biochemistry
Mar 20, 2023
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123
COVID-19 has had a lasting global health impact that continues to challenge the health care system. As the coronavirus continues to mutate, the current COVID-19 prevention strategies are plagued with supply chain disruptions, ...
Biochemistry
Nov 29, 2022
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32
Northwestern Medicine investigators have solved a challenging protein design puzzle using a unique high-throughput approach, according to a study published in Proceedings of the National Academy of Sciences.
Molecular & Computational biology
Oct 28, 2022
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90
Over the past two years, machine learning has revolutionized protein structure prediction. Now, three papers in Science describe a similar revolution in protein design.
Molecular & Computational biology
Sep 15, 2022
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2632
It may seem counterintuitive to many, but metal ions play a critical role in life, carrying out some of the most important biological processes. Think of hemoglobin—a metalloprotein responsible for carrying oxygen to the ...
Biochemistry
Mar 4, 2022
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89
Scientists at EMBL Hamburg and CSSB have determined the molecular structure of a gut protein that helps us absorb many drugs. This could help to develop drugs that reach target tissues more efficiently.
Molecular & Computational biology
Nov 3, 2021
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70
A team from Japan and the United States has identified the design principles for creating large 'ideal' proteins from scratch, paving the way for the design of proteins with new biochemical functions. Their results appear ...
Molecular & Computational biology
Jun 24, 2021
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6
Origami may sound more like art than science, but a complex folding pathway that proteins use to determine their shape has been harnessed by molecular biologists, enabling them to build some of the most complex synthetic ...
Molecular & Computational biology
Apr 12, 2021
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15
In a milestone for biomolecular design, a team of scientists has succeeded in creating new proteins that adopt one of the most complex folds known to molecular biology. These designer proteins were shown in the lab to spontaneously ...
Molecular & Computational biology
Feb 18, 2021
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