HSPC 'seeds' reveal VCAM-1+ macrophage role in homing process

Hematopoietic stem and progenitor cells (HSPCs) give rise to all blood lineages that support life. HSPCs, like seeds, need a suitable microenvironment to maintain their function. A process called "homing" allows HSPCs to ...

The gene code of growing limbs

When a fetus develops, cell division and differentiation, gene expression, cell-to-cell signaling, and morphogenesis must be carefully coordinated to occur in the correct sequence and for the proper amount of time. Failures ...

Single-cell database to propel biological studies

A team at Whitehead Institute and MIT has harnessed single-cell technologies to analyze over 65,000 cells from the regenerative planarian flatworm, Schmidtea mediterranea, revealing the complete suite of actives genes (or ...

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Progenitor cell

Like stem cells, progenitor cells have a capacity to differentiate into a specific type of cell. In contrast to stem cells, however, they are already far more specific: they are pushed to differentiate into their "target" cell. The most important difference between stem cells and progenitor cells is that stem cells can replicate indefinitely, whereas progenitor cells can only divide a limited number of times. Controversy about the exact definition remains and the concept is still evolving.

Despite the difficulty of defining progenitors, the term is frequently used in research. Thus, the importance of progenitors cannot be ignored.

The terms "progenitor cell" and "stem cell" are sometimes equated.

This text uses material from Wikipedia, licensed under CC BY-SA