In a recent study published in iScience, researchers have optimized the Tet-On system to improve the efficiency of generating skeletal muscle cells and other differentiated cell types from iPSCs for various basic and clinical ...
Cell & Microbiology
Oct 12, 2023
0
1
During the first hours of an embryo's development, specialized molecules called pioneer transcription factors unravel parts of its DNA to activate the encoded genes. Which gene is activated and when has to follow a set schedule ...
Cell & Microbiology
Sep 28, 2023
0
1
In-vitro culture of biological cells plays an important role in advancing biological research. However, currently available cell culture materials have significant drawbacks. Many of them are derived from animal sources, ...
Bio & Medicine
Aug 15, 2023
0
59
Gastrulation, the process where an embryo reorganizes itself from a hollow sphere into a multilayered structure, is considered a "black box" of human development. This is because human embryos are typically not cultured for ...
Cell & Microbiology
Jul 20, 2023
0
45
As a human embryo grows, a set of molecules directs cells as they multiply and take on specific identities and spatial positions within the embryo. In one crucial step known as gastrulation, these signaling molecules guide ...
Cell & Microbiology
Jul 17, 2023
0
34
In a groundbreaking study, researchers have unlocked a new frontier in the fight against aging and age-related diseases. The study, conducted by a team of scientists at Harvard Medical School, has published the first chemical ...
Cell & Microbiology
Jul 13, 2023
3
761
In humans, pregnancy lasts around nine months. In mice, only 20 days, and in rhinoceroses, as long as 17 months. Although many mammalian species go through the same stages during embryo development, the speed of development ...
Plants & Animals
Jun 20, 2023
0
17
A high-throughput single-cell single-mitochondrial genome sequencing technology known as iMiGseq has provided new insights into mutations of mitochondrial DNA (mtDNA) and offers a platform for assessing mtDNA editing strategies ...
Cell & Microbiology
Apr 13, 2023
0
45
Researchers have spotted how specific proteins within the chromosomes of roundworms enable their offspring to produce specialized cells generations later, a startling finding that upends classical thinking that hereditary ...
Cell & Microbiology
Apr 7, 2023
0
381
A team led by Masaya Hagiwara of RIKEN national science institute in Japan has developed an ingenious device, using layers of hydrogels in a cube-like structure, that allows researchers to construct complex 3D organoids without ...
Cell & Microbiology
Apr 7, 2023
0
89
