Almond and peach tree genomes shed light on their differences

Humans have been eating peaches and almonds for thousands of years. Although at first sight the products of these trees may seem to be very different, both species are part of the Prunus genus, and are genetically very similar—so ...

Orchestrating development in the fly embryo

Most multicellular organisms on Earth—including you—begin as a single fertilized egg and then undergo a complex choreography of cellular growth to become a functioning adult composed of countless cells. Understanding ...

Researchers identify the source of asymmetry in RNA-DNA hybrids

A study headed by the Institute for Research in Biomedicine (IRB Barcelona) and published in the journal CHEM furthers the understanding of the asymmetry between nucleic acid hybrids. This advance may make a significant contribution ...

A model to decipher the complexity of gene regulation

How, where and when genes are expressed determine individual phenotypes. If gene expression is controlled by many regulatory elements, what, ultimately, controls them? And how does genetic variation affect them? The SysGenetiX ...

Project reveals genome of celebrity cat Lil BUB

Lil BUB has drawn millions of followers across the internet for her cute appearance. Behind the celebrity cat's unique features is a combination of two rare genetic variants, three molecular biologists from Germany and the ...

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Regulation of gene expression

Gene modulation redirects here. For information on therapeutic regulation of gene expression, see therapeutic gene modulation.

Regulation of gene expression (or gene regulation) includes the processes that cells and viruses use to turn the information in genes into gene products. Although a functional gene product may be an RNA or a protein, the majority of known mechanisms regulate protein coding genes. Any step of the gene's expression may be modulated, from DNA-RNA transcription to the post-translational modification of a protein.

Gene regulation is essential for viruses, prokaryotes and eukaryotes as it increases the versatility and adaptability of an organism by allowing the cell to express protein when needed. The first discovered example of a gene regulation system was the lac operon, discovered by Jacques Monod, in which protein involved in lactose metabolism are expressed by E.coli only in the presence of lactose and absence of glucose.

Furthermore, gene regulation drives the processes of cellular differentiation and morphogenesis, leading to the creation of different cell types in multicellular organisms where the different types of cells may possess different gene expression profiles though they all possess the same genome sequence.

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