The complex architecture of bone is challenging to recreate in the lab. Therefore, advances in bone tissue engineering (BTE) aim to build patient-specific grafts that assist bone repair and trigger specific cell-signaling ...
A study in the journal Cell sheds new light on the evolution of neurons, focusing on the placozoans, a millimeter-sized marine animal. Researchers at the Center for Genomic Regulation in Barcelona find evidence that specialized ...
Evolution
Sep 19, 2023
1
170
Researchers hope to design a new generation of drugs against an array of deadly diseases. The task, however, is costly, arduous and often ineffective. One of the key challenges is understanding a particular class of proteins ...
Biochemistry
Apr 5, 2017
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109
(Phys.org)—The market value for deuterated drugs has recently been estimated at over a billion dollars. Such drugs are simply molecules in which one or more hydrogen atoms are replaced with deuterium. While these kinds ...
Two Americans won the Nobel Prize in chemistry Wednesday for studies of how the cells in our bodies pick up signals as diverse as hormones, smells, flavors and light—work that is key to developing better medicines.
Biochemistry
Oct 10, 2012
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0
Many drug and antibody discovery pathways focus on intricately folded cell membrane proteins: when molecules of a drug candidate bind to these proteins, like a key going into a lock, they trigger chemical cascades that alter ...
Biotechnology
Jun 21, 2024
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39
A group of researchers at University of California San Diego has identified the cause of a "short-circuit" in cellular pathways, a discovery that sheds new light on the genesis of a number of human diseases.
Cell & Microbiology
Jun 4, 2024
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81
An international team of researchers has succeeded in "filming" the activation of an important receptor. They froze the involved molecules at different points in time and photographed them under the electron microscope. They ...
Molecular & Computational biology
Mar 13, 2024
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76
Drug development is currently an extremely long, expensive and inefficient process. Findings generated in a lab are often very hard to replicate once translated into animal models or in humans.
Biotechnology
Feb 26, 2024
0
21
Peptides are biomolecules formed when two or more amino acids that perform key functions in the human organism, such as hormones, neurotransmitters, painkillers and antibiotics, bind together. For this reason, they are much ...
Biochemistry
Nov 1, 2023
1
25
