Preventing a genetic uprising in early life

Molecules called endosiRNAs help us avoid genetic chaos, according to a new study from a team at the Babraham Institute. Much of the human genome contains pieces of DNA called transposons, a form of genetic parasite. When ...

Stem cell laboratory in a bag

Human stem cells are considered a major new hope in the field of medicine. In the future, it is expected that they will make it possible to treat a wide range of ailments such as neurodegenerative diseases. With LabBag, Fraunhofer ...

Researchers reveal how stem cells make decisions

Embryonic stem cells have the remarkable ability to develop into any type of cell. On their way to become for example a liver or a heart cell, they must repeatedly decide between alternative developmental paths. How they ...

Understanding key enzyme's role in embryonic development

The catalytic activity of an enzyme called Set1A—a protein that is essential to the viability of embryonic stem cells (ESCs)—is not required for ESC self-renewal, according to a Northwestern Medicine study published in ...

A biobank of reversible mutant embryonic stem cells

Scientist at IMBA developed a biobank of revertible, mutant embryonic stem cells, published in the current issue of Nature. This cell bank – called Haplobank - contains over 100,000 mutated, conditional mouse embryonic ...

A new role for insulin as a vital factor in maintaining stem cells

New research conducted at the stem cell centre, DanStem, at the University of Copenhagen shows that insulin is a key determinant of embryonic stem cell potency in mammals. When large amounts of Insulin are around, stem cells ...

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