How genes share their workspace

Layers of gene control allow DNA to flexibly add new information. Genes and their genetic switches are organized into functional units to turn genes on or off just as needed. Disrupting these units can lead to disease, but ...

New advances in stem-cell derived mouse embryo model

Just two weeks after announcing the development of a mouse embryo model, complete with beating hearts and the foundations for a brain and other organs, from mouse stem cells, researchers in the laboratory of Magdalena Zernicka-Goetz, ...

First mouse model with mitochondrial tRNALeu mutation developed

Studying the role of mitochondria—the specialized structures within cells responsible for energy production—in metabolic diseases has been difficult because of a lack of animal models with the necessary mitochondrial ...

The chemical controlling life and death in hair follicles

A single chemical is key to controlling when hair follicle cells divide, and when they die. This discovery could not only treat baldness, but ultimately speed wound healing because follicles are a source of stem cells.

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