Scripps Research scientists have developed a new strategy for identifying small molecules that can change the function of proteins, offering a promising path for discovering targeted drugs. In collaboration with scientists ...
Biochemistry
Apr 27, 2023
0
54
Human lifespan is related to the aging of our individual cells. Three years ago a group of University of California San Diego researchers deciphered essential mechanisms behind the aging process. After identifying two distinct ...
Cell & Microbiology
Apr 27, 2023
1
500
Protists, a broad class of generally single-celled organisms that includes algae and amoebae, have long been regarded as a "catch-all" category for diverse microorganisms. Because of their diversity and prevalence, protists ...
Cell & Microbiology
Apr 27, 2023
0
3
Single-cell RNA-sequencing (scRNA-seq) technologies offer the opportunity to understand regulatory mechanisms at single-cell resolution. Gene regulatory networks (GRNs) provide a crucial blueprint of regulatory mechanisms ...
Molecular & Computational biology
Apr 27, 2023
0
2
A "window to evolution" has opened after mathematicians uncovered the universal explanatory framework for how molecules interact with one another to adapt to new and variable conditions while maintaining tight control over ...
Mathematics
Apr 27, 2023
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65
Cancer is a complex systemic disease, with accompanying secondary effects that can result in debilitating effects on the human body. Cancer-associated skeletal muscle weakening or loss, also called "cancer cachexia," is a ...
Bio & Medicine
Apr 24, 2023
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8
Biological cells, whether free-living or part of a multicellular organism, have to perform hundreds of functions to survive, such as perceiving their environment, uptaking and metabolizing nutrients, regenerating decayed ...
Cell & Microbiology
Apr 24, 2023
0
31
New insight into proteins called "pioneer factors" helps to explain their unusual ability to open up the typically dense genetic material within our cells. This behavior makes the genetic material accessible for proteins ...
Cell & Microbiology
Apr 20, 2023
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20
DNA replication is the process whereby cells make an exact copy of their DNA before cell division. A key part of the intricate DNA replication machinery is a molecular motor called CMG, which has the vital task of separating ...
Biotechnology
Apr 20, 2023
0
242
A hitherto unknown mechanism for DNA folding is described in a study in Nature published by researchers from Karolinska Institutet and the Max Planck Institute for Biophysics. Their findings provide new insights into chromosomal ...
Cell & Microbiology
Apr 19, 2023
0
21
