Engineers use 'DNA origami' to identify vaccine design rules

By folding DNA into a virus-like structure, MIT researchers have designed HIV-like particles that provoke a strong immune response from human immune cells grown in a lab dish. Such particles might eventually be used as an ...

MIB2 enhances inflammation by degradation of CYLD

A team of researchers at Ehime University revealed that E3 ubiquitin ligase MIB2 enhances inflammation by degrading the deubiquitinating enzyme CYLD. This finding was published on Sept. 20 in the Journal of Biological Chemistry.

How an emerging tick-borne pathogen evades detection

Human babesiosis is an emerging infectious disease transmitted to humans by ticks. A team of Yale researchers has discovered how Babesia microti, one of the two Babesia parasite species that transmit the disease in the United ...

Frog fungus fights back

Amphibian populations have been declining around the world for more than 40 years. One culprit is the fungus B. dendrobatidis, which causes the disease chytridiomycosis.

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B cell

B cells are lymphocytes that play a large role in the humoral immune response (as opposed to the cell-mediated immune response, which is governed by T cells). The principal functions of B cells are to make antibodies against antigens, perform the role of Antigen Presenting Cells (APCs) and eventually develop into memory B cells after activation by antigen interaction. B cells are an essential component of the adaptive immune system.

The abbreviation "B", in B cell, comes from the bursa of Fabricius in birds, where they mature. In mammals, immature B cells are formed in the bone marrow.

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