Chimeric antigen receptors (CARs) are synthesized membrane proteins that enable lymphocytes to recognize and respond to the specific antigens of target cells. Despite the impressive efficacy of CAR-T cell therapy in treating ...
Bio & Medicine
Mar 15, 2024
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7
Using a virus-like delivery particle made from DNA, researchers from MIT and the Ragon Institute of MGH, MIT, and Harvard have created a vaccine that can induce a strong antibody response against SARS-CoV-2.
Bio & Medicine
Jan 30, 2024
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104
We tend to just think of viruses in terms of their damaging impacts on human health and lives. The 1918 flu pandemic killed around 50 million people. Smallpox claimed 30% of those who caught it, and survivors were often scarred ...
Cell & Microbiology
Jan 10, 2024
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1
A recent study led by Professor Weiqi Zhang, affiliated with the Beijing Institute of Genomics, Chinese Academy of Sciences, and the China National Center for Bioinformation, in collaboration with Professors Guang-Hui Liu ...
Cell & Microbiology
Dec 20, 2023
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1
Upon infection or immunization, all jawed vertebrate species generate proteins called antibodies that bind and neutralize pathogens. Strong and long-lasting antibody responses in warm-blooded species such as mammals are produced ...
Molecular & Computational biology
Dec 1, 2023
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35
Recently, the team of Academician Huang Wei, Professor Li Lin and Professor Hu Wen Bo from the School of Northwestern Polytechnical University developed an ultra-efficient NIR-II photothermal agent for 1,064 nm laser-mediated ...
Bio & Medicine
Oct 30, 2023
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1
B cells or B lymphocytes are an important part of the body's immune system. When healthy B cells are infected with the Epstein-Barr virus (EBV), they undergo growth transformation, a process that immortalizes B cells, leading ...
Cell & Microbiology
Aug 7, 2023
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17
Chemotherapy and radiotherapy aim to destroy cancer cells by inducing DNA double-strand breaks—damage that, once inflicted, usually causes the cells to die. But damage to a cell's genetic material also activates a signaling ...
Biochemistry
Jul 27, 2023
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61
Researchers at NCMM have demonstrated the mechanisms behind the activation of Aurora B, a central conductor of cell division. Their findings, now published in eLife, can lay the foundations for developing new cancer drugs.
Cell & Microbiology
Jul 6, 2023
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34
Researchers in the Salinas Lab in The University of New Mexico's Department of Biology have discovered an immune structure in the nasal cavities of rainbow trout that scientists previously didn't know existed. The new knowledge ...
Plants & Animals
Dec 14, 2022
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51
B cells are lymphocytes that play a large role in the humoral immune response (as opposed to the cell-mediated immune response, which is governed by T cells). The principal functions of B cells are to make antibodies against antigens, perform the role of Antigen Presenting Cells (APCs) and eventually develop into memory B cells after activation by antigen interaction. B cells are an essential component of the adaptive immune system.
The abbreviation "B", in B cell, comes from the bursa of Fabricius in birds, where they mature. In mammals, immature B cells are formed in the bone marrow.
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