Detection of a new state in the protein folding process

Scientists have discovered a new, intermediate state in the process of protein folding, showing folding can occur in two stages, one fast and the next found to be much slower. The findings are published in the journal Physical ...

Decoding a key part of the cell, atom by atom

Whatever you are doing, whether it is driving a car, going for a jog, or even at your laziest, eating chips and watching TV on the couch, there is an entire suite of molecular machinery inside each of your cells hard at work. ...

Freeze frame: Researchers solve how cells unfold proteins

A happy cell is a balanced cell, but for every stupendously twisted protein it creates, it must tear the old ones asunder. That means untangling a convoluted pretzel-like mass for recycling. Cdc48 plays a critical role in ...

Defying textbook science, study finds new role for proteins

Open any introductory biology textbook and one of the first things you'll learn is that our DNA spells out the instructions for making proteins, tiny machines that do much of the work in our body's cells. Results from a study ...

New step in DNA damage response in neurons discovered

Researchers have identified a biochemical switch required for nerve cells to respond to DNA damage. The finding, scheduled for advance online publication in Nature Cell Biology, illuminates a connection between proteins involved ...

Discovery reveals lipid-signaling microdomains in cells

Important signaling molecules called phospholipids are active throughout cells in small compartments called condensates, rather than functioning primarily in cell membranes as previously thought, according to a study from ...

Unleashing the power of AI to track animal behavior

Movement offers a window into how the brain operates and controls the body. From clipboard-and-pen observation to modern artificial intelligence-based techniques, tracking human and animal movement has come a long way. Current ...

Reading out RNA structures in real time

Amyotrophic lateral sclerosis (ALS), commonly known as Lou Gehrig's disease and Stephen Hawking's disease, is a neurodegenerative disease that results in the gradual loss of control over the muscles in the body. It is currently ...

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