A new horizon for vibrational circular dichroism spectroscopy

A new horizon for vibrational circular dichroism spectroscopy
Time-step VCD measured monitoring in situ the progress of chirality amplification from microscopic to supramolecular scales. Credit: Royal Society Of Chemistry

Vibrational circular dichroism (VCD) spectroscopy is an extension of circular dichroism spectroscopy into the infrared and near-infrared regions where vibrational transitions occur in the ground electronic state of a molecule. The method offers the advantage of studying the chiroptical properties of a wide range of molecules in non-crystalline states.

However, due to the weakness of the signals, one measurement requires several hours to yield reliable results. Accordingly, its target was limited to a stable molecule in a solution. To overcome this difficulty, our group applied the VCD method to supramolecular systems. In this article, we report a new horizon for VCD spectroscopy. Solid state and time-step VCD methods were developed in determining the mechanism of chirality amplification from the microscopic to supramolecular scales.

The VCD signals were enhanced in the following three cases: (i) chiral gels with hundreds of molecules arranged in stereoregularity, (ii) chiral metal complexes with low-lying in the IR region, and (iii) a molecular pair interacting stereoselectively on a . Finally, we describe an on-going project involving the construction of a multi-dimensional VCD system.

Explore further

Chirality in real time

More information: Sina Wrede et al. Towards sustainable and eļ¬ƒcient p-type metal oxide semiconductor materials in dye-sensitised photocathodes for solar energy conversion, Physical Chemistry Chemical Physics (2020). DOI: 10.1039/D0CP01363C
Provided by Ehime University
Citation: A new horizon for vibrational circular dichroism spectroscopy (2020, May 29) retrieved 11 July 2020 from https://phys.org/news/2020-05-horizon-vibrational-circular-dichroism-spectroscopy.html
This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only.

Feedback to editors

User comments