UCSD chemists produce first high-resolution RNA 'nano square'
Chemists at UC San Diego have produced the first high resolution structure of a nano-scale square made from ribonucleic acid, or RNA.
The structure was published in a paper in this week's early online edition of the journal Proceedings of the National Academy of Sciences by a team of chemists headed by Thomas Hermann, an assistant professor of chemistry and biochemistry at UCSD.
The nano square self-assembles from four corner units directed by the sequence that was programmed into the RNA used for preparing the corners.
Hermann said the RNA square has potential applications as a self-assembling nano platform for the programmed combination of molecular entities that are linked to the corner units.