Ubiquitin ligases regulate many processes in living cells. Depending on how many ubiquitin molecules they attach to the target proteins and in which way, they control the protein's fate.
Cell & Microbiology
Feb 8, 2024
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For decades it has been an open question in the ubiquitin research field how proteins are labeled as being defective or unneeded. In a recent study Brenda Schulman, Director at the Max Planck Institute (MPI) of Biochemistry, ...
Cell & Microbiology
Feb 7, 2024
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1
Scientists at City of Hope, one of the largest cancer research and treatment organizations in the United States, have discovered a new cellular mechanism that plays an important role in cancer cells' ability to cause disease. ...
Cell & Microbiology
Feb 5, 2024
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73
A recent re-emergence and outbreak of mpox brought poxviruses back as a public health threat, underlining an important knowledge gap at their core. Now, a team of researchers from the Institute of Science and Technology Austria ...
Molecular & Computational biology
Feb 5, 2024
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7
A team of researchers has developed an innovative method to design complicated all-α proteins, characterized by their non-uniformly arranged α-helices as seen in hemoglobin. Employing their novel approach, the team successfully ...
Molecular & Computational biology
Jan 4, 2024
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61
In a complex called chromatin, long strands of DNA in cells' nuclei are tightly wrapped around a scaffolding of proteins, like a rolled-up ball of yarn. A new study by Weill Cornell Medicine investigators reveals that beyond ...
Cell & Microbiology
Jan 2, 2024
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70
A research group led by Professor Nobuo Noda of Hokkaido University has reconstituted the membrane invagination process required to form autophagosomes in vitro for the first time, showing that this process is mediated by ...
Molecular & Computational biology
Dec 20, 2023
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2
Cell biologists from RIKEN have provided an unprecedented glimpse into the distinctive features of an unusual chromosome—the inactivated X chromosome copy carried by every female cell. The findings are published in the ...
Cell & Microbiology
Nov 14, 2023
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54
Depression, obesity or chronic pain—all of these disorders can be triggered or promoted by stress. In two publications, researchers at TU Darmstadt show new ways of treating stress-related diseases.
Biochemistry
Nov 10, 2023
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53
Scientists have breathed new life into the study of a protein with an outsized link to human cancers because of its dangerous mutations, using advanced research techniques to detect its hidden regions.
Cell & Microbiology
Oct 18, 2023
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