Researchers reveal architecture of the ESCPE-1 membrane coat

A common activity in our daily household chores is separating paper, glass, cans, and plastic to deposit them in the appropriate containers. Through recycling, we can reduce resource consumption, save energy, and minimize ...

How the ancient messengers cAMP and cGMP deliver their messages

Two highly similar molecules with essential but often contrasting signaling roles in most life forms exert their distinct effects through subtle differences in their bindings to their signaling partners, according to a new ...

Structural insight into process of gene regulation

In the cell nucleus, numerous proteins bind to the DNA molecule in order to regulate the activity of certain genes. One of these is the TATA-box binding protein (TBP), which binds to a specific DNA sequence and constitutes ...

X-file cracked: Mini-key determines DNA shape

We finally know why our DNA has an X shape. This finding by researchers at the Netherlands Cancer Institute may have much broader implications for how our cells behave. "It looks like we have uncovered a universal mechanism ...

A molecular machine's secret weapon exposed

RNAs are having a moment. The foundation of COVID-19 vaccines, they've made their way from biochemistry textbooks into popular magazines and everyday discussions. Entire companies have been launched that are dedicated to ...

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