A research team led by Prof. Zhao Guoping from the Hefei Institutes of Physical Science (HFIPS) of the Chinese Academy of Sciences (CAS) has proposed a mechanism by which protein disulfide isomerase (PDI) can translocate ...
Cell & Microbiology
Oct 17, 2022
0
6
The equilibrium between reducing species and oxidizing species within the tumor microenvironment (TME) plays a crucial role in a majority of biological processes, especially the apoptotic cell death process. When the balance ...
Bio & Medicine
Oct 13, 2022
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5
The enzyme HDAC10 is involved in a variety of cellular processes associated with the development of a number of diseases. However, it is often not known exactly what role HDAC10 plays in the disease process. Scientists from ...
Biochemistry
Oct 12, 2022
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28
Metal-containing complexes have taken up center stage in the search for new cancer drugs that are as free of side effects as possible. In the journal Angewandte Chemie, a research team has now described how a very low dose ...
Biochemistry
Oct 12, 2022
0
44
Cancer is the second leading cause of death in Switzerland. Among the different types of cancers, non-small cell lung cancer (NSCLC) kills the most patients and remains largely incurable. Unfortunately, even newly approved ...
Cell & Microbiology
Oct 6, 2022
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68
Researchers at the Paul Scherrer Institute PSI, in collaboration with ETH Zurich, have optimized a method for tumor diagnosis using radionuclides. Potential side-effects can now be significantly reduced through a molecular ...
Biochemistry
Oct 4, 2022
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4
Stanford University researchers have discovered a rapid and sustainable way to synthetically produce a promising cancer-fighting compound right in the lab. The compound's availability has been limited because its only currently ...
Biochemistry
Oct 3, 2022
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128
Carrier-free multi-component self-assembled nano-systems have attracted widespread attention owing to their easy preparation, high drug-loading efficiency, and excellent therapeutic efficacy. In an article recently published ...
Bio & Medicine
Sep 26, 2022
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5
One approach to treating cancer is photodynamic therapy using photo-uncaging systems, in which light is used to activate a cancer-fighting agent in situ at the tumor. However, suitable agents must be stable under visible ...
Biochemistry
Sep 20, 2022
0
104
Newly discovered genetic commonalities and differences among the most prevalent types of canine soft tissue sarcomas, a common and potentially deadly tumor, could pave the way for more accurate diagnosis and better treatments ...
Veterinary medicine
Sep 14, 2022
0
5
