Several diseases, including certain types of cancer and some neurodevelopmental conditions, have aberrant patterns of DNA methylation, a chemical modification that regulates gene expression in ways that keep genes in the ...
Cell & Microbiology
Dec 6, 2022
0
6
The brains of all higher-order animals are filled with a diverse array of neuron types, with specific shapes and functions. Yet, when these brains form during embryonic development, there is initially only a small pool of ...
Cell & Microbiology
Nov 29, 2022
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100
Some of the toughest challenges in treating disease are presented by "undruggable" proteins whose structures and roles in disease are known but are seemingly unable to be targeted by drugs that will bind to them. Researchers ...
Molecular & Computational biology
Nov 21, 2022
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33
Maize (Zea mays) is an important food, feed, and bioenergy crop that plays a pivotal strategic role in food security, while insect pests seriously affect the yield and quality of maize. Benzoxazinoids (BXDs) and volatile ...
Molecular & Computational biology
Nov 16, 2022
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5
Jasmonate is a critical phytohormone that regulates plant development and adaptation to external conditions. In response to an exposure biotic or abiotic stress, jasmonate accumulates in plants, leading to root growth inhibition ...
Plants & Animals
Nov 14, 2022
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25
For decades, cancer researchers have longed for a way to target a set of proteins called transcription factors. While we've long known that tumors use these proteins to grow out of control, their unique configurations meant ...
Biotechnology
Nov 3, 2022
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14
Hypoxia (oxygen deficiency), in addition to occurring in areas of considerable altitude, is a critical factor linked to various cardiopulmonary diseases of high morbidity and mortality in humans. The carotid body, a highly ...
Cell & Microbiology
Nov 3, 2022
0
25
Using an approach based on CRISPR proteins, MIT researchers have developed a new way to precisely control the amount of a particular protein that is produced in mammalian cells.
Biotechnology
Nov 1, 2022
0
28
The changes that occur in fleshy fruits during ripening make them more sensitive than unripe fruit to infection by bacteria and fungi. The challenge for fruit production is to balance fruit ripening and pathogen resistance ...
Cell & Microbiology
Oct 25, 2022
0
16
There is a tightly regulated balance between cell growth and death in healthy tissue. The loss of this balance is essentially what initiates cancer.
Cell & Microbiology
Oct 19, 2022
0
2
