Researchers reprogram T cells to improve cancer immunotherapy

St. Jude Children's Research Hospital scientists have identified a new therapeutic strategy that enhanced cancer immunotherapy, slowed tumor growth and extended the lives of mice with cancer. The research appears today in ...

Study reveals dynamics of crucial immune system proteins

Of the many marvels of the human immune system, the processing of antigens by the class I proteins of the major histocompatability complex (MHC-I) is among the most mind-boggling. Exactly how these proteins carry out their ...

Researchers use immune system to attack glioblastoma

The Yale laboratory of Sidi Chen, assistant professor of genetics in the Systems Biology Institute and Yale Cancer Center, has developed advanced gene-editing and screening technology to find new targets for cancer immunotherapy.

Mother cells as organelle donors

Microbiologists at LMU and UoG have discovered a recycling process in the eukaryotic parasite Toxoplasma gondii that plays a vital role in the organism's unusual mode of reproduction.

Successful T cell engineering with gene scissors

The idea of genetically modifying a patient's own immune cells and deploying them against infections and tumors has been around since the 1980s. But to this day modified T cells are still not as effective as natural T cells ...

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