'Cannibalism' is a double-whammy for cell health

Certain Inflammatory and infectious diseases, such as hardening arteries and tuberculosis, are caused by the build-up inside immune cells of harmful substances, such as cholesterol and bacteria. A study published today by ...

Scientists develop technology to capture tumor cells

Instead of searching for a needle in a haystack, what if you were able to sweep the entire haystack to one side, leaving only the needle behind? That's the strategy researchers in the University of Georgia College of Engineering ...

Research paves way for new source for leukemia drug

Chemistry researchers at Oregon State University have patented a method for making anti-leukemia compounds that until now have only been available via an Asian tree that produces them.

On the origin of B1 cells

A new MDC study may resolve a decades-old debate in immunology. A team led by Professor Klaus Rajewsky reports in Science that distinct progenitor cells are not required for the development of B1 cells. Instead, the team's ...

Spotlight on Space Station science

hough all ESA astronauts are back on Earth, European science on the International Space Station is ongoing. Explore a few experiments underway right now in celebration of science at ESA.

A new molecular player involved in T cell activation

When bacteria or viruses enter the body, proteins on their surfaces are recognized and processed to activate T cells, white blood cells with critical roles in fighting infections. During T-cell activation, a molecular complex ...

Mice display altered immune system following spaceflight

New research published in The FASEB Journal brings to light new information regarding the increased susceptibility of mice to infection during spaceflight. Based on examinations of mice that had been on board the Bion-M1 ...

Discovery could neutralize West Nile virus

Researchers at Vanderbilt University Medical Center and colleagues have isolated a human monoclonal antibody that can "neutralize" the West Nile virus and potentially prevent a leading cause of viral encephalitis (brain inflammation) ...

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White blood cell

White blood cells (WBCs), or leukocytes (also spelled "leucocytes"), are cells of the immune system defending the body against both infectious disease and foreign materials. Five different and diverse types of leukocytes exist, but they are all produced and derived from a multipotent cell in the bone marrow known as a hematopoietic stem cell. Leukocytes are found throughout the body, including the blood and lymphatic system.

The number of leukocytes in the blood is often an indicator of disease. There are normally between 4×109 and 1.1×1010 white blood cells in a litre of blood, making up approximately 1% of blood in a healthy adult. An increase in the number of leukocytes over the upper limits is called leukocytosis, and in leukopenia, this number is much lower than the lower limit. The physical properties of leukocytes, such as volume, conductivity, and granularity, may change due to activation, the presence of immature cells, or the presence of malignant leukocytes in leukemia.

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