How cells manage their mRNA stockpile and its output

In a typical cell, genes encoded in DNA are used to make messenger RNA (mRNA), which is used to make proteins, and this process of gene expression keeps the cell running. Gene expression is regulated in each cell such that ...

Junk DNA in birds may hold key to safe, efficient gene therapy

The recent approval of a CRISPR-Cas9 therapy for sickle cell disease demonstrates that gene editing tools can do a superb job of knocking out genes to cure hereditary disease. But it's still not possible to insert whole genes ...

Important molecular pathway for control of aging discovered

One of the ways cells in different kinds of tissue communicate is by exchanging RNA molecules. In experiments with roundworms of the species Caenorhabditis elegans, researchers at the State University of Campinas (UNICAMP) ...

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