A research team lead by MIMS/SciLifeLab research group leader Jonas Barandun, Umeå University, Sweden, uses cryo-electron microscopy to provide near atomic details of the smallest known eukaryotic cytoplasmic protein synthesis ...
Cell & Microbiology
Jul 22, 2019
0
157
Microbes are master chefs of the biomolecular world; collectively, they harbor the ability to produce a vast array of unknown substances, some of which may have therapeutic or other useful properties. In searching for useful ...
Biotechnology
Jul 19, 2019
0
143
Ribosomes, the essential machinery used for protein synthesis is recycled after each one round of translation. An enzyme called ABCE1 is responsible for this process and turns out to be remarkably plastic as LMU biophysicists ...
Cell & Microbiology
Jul 18, 2019
0
104
Bacterial ribosomes need a single-stranded ribosome binding site (RBS) to initiate protein synthesis, whereas stable RNA structure blocks initiation. Paradoxically, structured mRNAs can nevertheless be efficiently translated. ...
Cell & Microbiology
Jul 15, 2019
0
229
Protein aggregates are toxic for mitochondrial function, and thus disrupt the supply of chemical energy to their host cells. An LMU team has characterized a protein complex that prevents the build-up of such deposits in the ...
Cell & Microbiology
Jun 24, 2019
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1
Microorganisms often assemble natural products similar to product assembly lines. Certain enzymes, non-ribosomal peptide synthetases (NRPS), play a key role in this process. Biotechnologists at Goethe University have now ...
Biochemistry
Jun 12, 2019
0
14
Groundbreaking research at the new long-wavelength macromolecular crystallography beamline (I23) at Diamond Light Source has for the first time demonstrated the location of potassium ions in bacterial ribosomes. Ribosomes ...
Biochemistry
Jun 7, 2019
0
163
Researchers from Marvin Tanenbaum's group at the Hubrecht Institute have shown that translation of the genetic information stored in our DNA is much more complex than previously thought. This discovery was made by developing ...
Cell & Microbiology
Jun 6, 2019
0
876
Researchers from the Stowers Institute for Medical Research have discovered a new function of ribosomes in human cells that may show the protein-making particle's role in destroying healthy mRNAs, the messages that decode ...
Molecular & Computational biology
May 24, 2019
1
420
A team of researchers at the RIKEN Center for Biosystems Dynamics Research in Japan has developed a tool to prevent neurogenerative diseases. They have demonstrated a way to observe the molecular mechanism that switches control ...
