Biophysicists from the MIPT Center for Molecular Mechanisms of Aging and Age-Related Diseases have teamed up with colleagues from Canada, the U.S., Japan, France, and Germany to shed light on the structure and functioning ...
Biotechnology
Jan 20, 2020
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56
If certain signaling cascades are misregulated, diseases like cancer, obesity and diabetes may occur. A mechanism recently discovered by scientists at the Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP) in ...
Cell & Microbiology
Aug 15, 2018
0
2
Alcohol use disorders can have devastating effects on a person's health, relationships and finances. Yet for some, the feeling they get when taking a drink temporarily outweighs these other concerns. Now, researchers have ...
Other
Aug 8, 2018
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2
Scientists at Heptares Therapeutics have published the first high-resolution X-ray crystal structure of the complement C5a receptor (a G protein-coupled receptor, GPCR) binding a small molecule allosteric antagonist.
Biochemistry
Jan 4, 2018
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7
An international team of scientists including from the University of Adelaide have identified potential inhibitors of specific cell membrane proteins, which are involved in the spread of cancer to other parts of the body ...
Biochemistry
Oct 15, 2015
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30
Using computer simulations to predict which drug candidates offer the greatest potential has thus far not been very reliable, because both small drug-like molecules and the amino acids of proteins vary so much in their chemistry. ...
Biochemistry
Apr 21, 2014
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0
"Pain begone!" In order to send out this signal, the human body produces tiny messenger molecules that dock to certain receptors. Using traditional biochemical methods, this interaction between the messengers, so-called enkephalins, ...
Biochemistry
Jul 9, 2013
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0
Normal vision is essentially a spatial sense that often relies upon touch and movement during and after development, there is often a correlation between how an object looks and how it feels. Moreover, as a child's senses ...
Engineering
May 1, 2013
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0
The body's cell machinery often attaches sugar chains onto proteins to create molecules that play a crucial role in everything from protective immunity to structural stability. However, distinguishing between the different ...
Analytical Chemistry
Nov 30, 2012
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0
Scientists studying longevity thought it might be good to lack a copy of a gene, called IGF1 receptor, that is important in insulin signaling. Previous studies showed invertebrates that lacked the copy lived longer, even ...
Biochemistry
Nov 23, 2011
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