A study from Patrick Matthias and his group at the FMI challenges a widely accepted model on how epigenome dynamics control the differentiation of hematopoietic cells. The plasticity of pluripotent stem cells was thought ...
Cell & Microbiology
Oct 20, 2015
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50
The master regulator of muscle differentiation, MyoD, functions early in myogenesis to help stem cells proliferate in response to muscle injury, according to researchers at Case Western Reserve University. The study appears ...
Cell & Microbiology
Jan 4, 2010
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Immune cells protect the host from infection by pathogens. They include monocytes, which are large white blood cells that can differentiate into scavenger cells macrophages and dendritic cells in response to inflammatory ...
Jun 15, 2017
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2
Germline stem and progenitor cells (GSPCs), including primordial germ cells (PGCs) and germline stem cells (GSCs), generate various states of germ stem cells and then differentiate into spermatozoa and ova to produce offspring. ...
Cell & Microbiology
Nov 11, 2022
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10
In a study published in Science Advances, a team led by Prof. Zheng Ping from Kunming Institute of Zoology of the Chinese Academy of Sciences (CAS), collaborating with the Prof. Meng Feilong from Shanghai Institute of Biochemistry ...
Molecular & Computational biology
Nov 6, 2020
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23
Not all adult stem cells are created equal. Some are busy regenerating worn out or damaged tissues, while their quieter brethren serve as a strategic back-up crew that only steps in when demand shoots up. Now, researchers ...
Cell & Microbiology
Jul 19, 2012
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The average human has about 37.2 trillion cells. But cells are differentiated for thousands of different functions. How does a cell 'know' which function to fulfill? In a paper published today in Developmental Cell, the group ...
Cell & Microbiology
Oct 12, 2017
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2
Maternal consumption of a Western-style diet alters the transcriptional landscape of fetal blood stem cells in rhesus macaques, researchers report November 3 in the journal Stem Cell Reports.
Plants & Animals
Nov 3, 2022
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47
A scientific study describes for the first time the function of a signalling pathway –particularly, the pathway of epidermal growth factor receptors (EGFR) - in the differentiation of the planarian digestive lineage. EGFR ...
Cell & Microbiology
May 20, 2016
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4
A readily available, inexpensive, small molecule drug can improve the fitness of hematopoietic stem and progenitor cells (HSPCs) that are modified outside the body, potentially improving the success of procedures such as ...
Cell & Microbiology
Sep 27, 2023
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