Related topics: patients · cells · cancer cells · protein

Synthesizing a deadly mushroom toxin

The death-cap mushroom has a long history as a tool of murder and suicide, going back to ancient Roman times. The fungus, Amanita phalloides, produces one of the world's deadliest toxins: α-amanitin. While it may seem ill-advised, ...

An improved anti-addiction medication

Drug addiction continues to plague vast numbers of people across the world, destroying and ending lives, while attempts to develop more effective pharmaceutical addiction treatments continue. Scientists now report in the ...

Nanoshells could deliver more chemo with fewer side effects

Researchers investigating ways to deliver high doses of cancer-killing drugs inside tumors have shown they can use a laser and light-activated gold nanoparticles to remotely trigger the release of approved cancer drugs inside ...

When HIV drugs don't cooperate

The term "synergy" has gained a reputation as an overused buzzword, but it has a quantifiable definition in pharmacology. Two drugs are considered synergistic when their effectiveness when used together is greater than the ...

Cellular 'garbage disposal' has another job

A subset of protein complexes whose role has long been thought to consist only of chemically degrading and discarding of proteins no longer needed by cells appears to also play a role in sending messages from one nerve cell ...

Enzyme key to learning in fruit flies

An animal's reaction to an odor or food or other stimuli depends largely on past experiences and how they have been entered into memory.

Probing the function of key proteins

"Kinase inhibitor" drugs, which target a class of enzymes that are crucial to keep cells running, make up one of the great success stories of modern medicine.

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