Studying diseases with better delivery of gene-editing tools

Stem cells can be used to study the effects of disease on numerous tissue types due to their pluripotency, or ability to produce cells of any type. But using gene-editing tools with them can be challenging, according to Xiaojun ...

How embryo cells gain independence

It happens in the first hours after fertilization: The cells of the early embryo begin to independently produce proteins, the building blocks for cells and organs. Their own, uniquely composed genetic material serves as the ...

Metabolism found to regulate production of killer cells

In a recent study from Lund University in Sweden, researchers discovered that metabolic changes affect how blood cells are formed during embryonic development. They found a previously unknown metabolic switch with a key role ...

Mutant stem cells defy rules of development

Imagine you're baking a cake, but you run out of salt. Even with the missing ingredient, the batter still looks like cake batter, so you stick it in the oven and cross your fingers, expecting to end up with something pretty ...

Stem cells organize themselves into embryoid

Researchers at the University of Bonn have developed a method to generate embryo-like cell complexes from the stem cells of mice. The method provides new insights into embryonic development. In the medium term, it might also ...

A missing genetic switch at the origin of embryonic malformations

Embryonic development follows delicate stages: For everything to go well, many genes must coordinate their activity according to a very meticulous scheme and tempo. This precision mechanism sometimes fails, leading to more ...

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