Fast folding for synthetic peptides and microproteins
Certain types of peptides and microproteins for drug discovery research can be made more efficiently and quickly using a reaction solvent that helps mimic nature's way.
Certain types of peptides and microproteins for drug discovery research can be made more efficiently and quickly using a reaction solvent that helps mimic nature's way.
Biochemistry
Mar 22, 2024
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Many important medicines, such as antibiotics and anticancer drugs, are derived from natural products of bacteria. The enzyme complexes that produce these active ingredients have a modular design that makes them ideal tools ...
Cell & Microbiology
Mar 21, 2024
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51
Polymer systems composed of multiple components can spontaneously induce emulsion or microdroplets by mechanical mixing, as an intermediate state of macroscopic phase separation. Unfortunately, the size of generated droplets ...
Polymers
Mar 20, 2024
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Teardrop-shaped particles designed to inactivate multiple strains of the SARS-CoV-2 virus could one day complement existing treatments for COVID-19, according to a new study led by researchers at the University of Michigan ...
Bio & Medicine
Mar 19, 2024
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51
The U.S. Food and Drug Administration has approved the first drug to treat yeast ear infections in dogs.
Cell & Microbiology
Mar 19, 2024
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A longstanding problem in physics has finally been cracked by Professor Kostya Trachenko of Queen Mary University of London's School of Physical and Chemical Sciences. His research, published in Physical Review E, unveils ...
General Physics
Mar 18, 2024
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Scientists in Canada and the U.S. have discovered a new way in which Ebola—an often deadly virus affecting people mostly in sub-Saharan Africa—reproduces in the body.
Molecular & Computational biology
Mar 17, 2024
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126
Since the revelation of poly(ADP-ribose) polymerase (PARP) inhibitors and their remarkable results in the treatment of BRCA1/2 mutant cancers, synthetic lethality (SL) in antitumor therapy has attracted increasing attention. ...
Bio & Medicine
Mar 14, 2024
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Semaglutide is part of the glucagon-like peptide-1 (GLP-1) receptor targeting family of peptide drugs which are mainly used to treat diabetes but are difficult and expensive to make.
Biochemistry
Mar 12, 2024
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68
Finding the best method to deliver chemotherapeutic drugs to tumor cells can be tricky. Ideally, the treatments target tumor cells while leaving healthy cells alone.
Bio & Medicine
Mar 12, 2024
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