If asked about clones, most people think of evil sci-fi characters. However, in real life, the word "clone" often has broader, far more positive applications. Just as office workers replicate documents by using copy machines, ...
Biotechnology
Oct 8, 2018
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14
Researchers from Tokyo Metropolitan University and the FIRC Institute of Molecular Oncology (IFOM) in Italy have succeeded in depleting AND-1, a key protein for DNA replication, by using a recently developed conditional protein ...
Cell & Microbiology
Oct 1, 2018
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70
DNA is a lengthy molecule—approximately 1,000-fold longer than the cell in which it resides—so it can't be jammed in haphazardly. Rather, it must be neatly organized so proteins involved in critical processes can access ...
Cell & Microbiology
Sep 18, 2018
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20
If you've ever seen a picture of a DNA molecule, you probably saw it in its famous B-form: two strands coiling around each other in a right-handed fashion to form a double helix. But did you know that DNA can change its shape?
Cell & Microbiology
Aug 30, 2018
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4
Researchers from Osaka University in Japan have uncovered a key control mechanism of DNA replication with potential implications for better understanding how cells maintain genetic information to prevent diseases or cancer.
Cell & Microbiology
Aug 16, 2018
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5
A new method allows researchers to systematically identify specialized proteins that unpack DNA inside the nucleus of a cell, making the usually dense DNA more accessible for gene expression and other functions. The method, ...
Cell & Microbiology
Jul 12, 2018
2
128
Cells propagate by making copies of themselves via genome replication. Arguably, replication of DNA is the most fundamental and conserved mechanism of all life forms. Cracking the secret of how this process is achieved with ...
Biochemistry
Jul 6, 2018
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5
For the first time, researchers have been able to use cryo-electron microscopy, to reveal the detailed structure of the common herpes virus.
Biochemistry
Jul 5, 2018
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112
Researchers at Karolinska Institutet, Sweden, and the University of Sussex, England, have discovered that the process of copying DNA generates a brake signal that stalls cell division. This molecular brake ensures that the ...
Cell & Microbiology
Jun 28, 2018
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3
The process of copying DNA is complex choreography that requires rapid speeds and pin-point precision. Discovering the intricate details of this process could identify new ways to target diseases, such as cancer, and KAUST ...
Biochemistry
Jun 4, 2018
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7
