Cryo-EM reveals structure and mechanism of the 5-HT3 receptor

In November 2017, a Titan Krios cryo-electron microscope (cryo-EM) was inaugurated at the ESRF, the European Synchrotron, France. Data collected on this cryo-EM features in a Nature publication describing the activation cycle ...

Flow of cerebrospinal fluid regulates division

Stem cells in the brain can divide and mature into neurons participating in various brain functions, including memory. In a paper scientists have discovered that the flow of cerebrospinal fluid is a key signal for neural ...

Electron microscope images reveal how cells absorb a vital mineral

Columbia University Medical Center (CUMC) researchers have obtained the first detailed snapshots of the structure of a membrane pore that enables epithelial cells to absorb calcium. The findings could accelerate the development ...

Saliva proteins could explain why some people overuse salt

Many Americans consume too much salt. Now in a study appearing in the Journal of Agricultural and Food Chemistry, scientists report that people who can easily taste salt have differing amounts of certain proteins in their ...

Flexibility is key in mechanism of biological self-assembly

A new study has modeled a crucial first step in the self-assembly of cellular structures such as drug receptors and other protein complexes, and found that the flexibility of the structures has a dramatic impact on how fast ...

Malaria mosquitos sensitive to horseradish

Researchers at Lund University in Sweden have taken an important step on the road to understanding the underlying mechanism of how and why animals can feel pain in connection with cold or heat. However, according to the study, ...

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