In about a fifth of the cases of Parkinson's disease, look to a small, malfunctioning protein in the lysosome as a risk factor, say University of Michigan researchers.
Cell & Microbiology
Jun 23, 2022
0
29
Using highly sensitive fluorescent probes, a team of scientists from the University of Connecticut has captured the never-before-seen structural dynamics of an important protein channel inside the cell's primary power plant ...
Cell & Microbiology
Jul 7, 2013
0
0
Many proteins with important biological functions are embedded in a biomembrane in the cells of humans and other living organisms. But how do they get in there in the first place? Researchers in the Department of Biosystems ...
Cell & Microbiology
Feb 15, 2019
1
63
EPFL scientists have elucidated for the first time how a notoriously elusive serotonin receptor functions with atom-level detail. The receptor transmits electrical signals in neurons and is involved in various disorders, ...
Biochemistry
Apr 21, 2016
0
42
The research labs of Dr. Thomas Becker and Dr. Nikolaus Pfanner from the Institute for Biochemistry and Molecular Biology at the University of Freiburg have reported a function of the metabolite channel of the mitochondrial ...
Cell & Microbiology
Feb 7, 2019
0
105
(PhysOrg.com) -- Mitochondria, those battery-pack organelles that fuel the energy of almost every living cell, have an insatiable appetite for calcium. Whether in a dish or a living organism, the mitochondria of most organisms ...
Biochemistry
Jun 19, 2011
2
0
In a feat that would have been unachievable only a few years ago, researchers at UC San Francisco have pulled aside the curtain on a protein informally known as the "wasabi receptor," revealing at near-atomic resolution structures ...
Biochemistry
Apr 8, 2015
0
60
Scientists have discovered that a human receptor protein has the ability to detect individual amino acids in exactly the same way that bacteria do.
Cell & Microbiology
Mar 1, 2022
0
214
(Phys.org)—The market value for deuterated drugs has recently been estimated at over a billion dollars. Such drugs are simply molecules in which one or more hydrogen atoms are replaced with deuterium. While these kinds ...
A study has solved a long-standing debate about the transport of essential proteins, implicated in many human diseases, through one of the cell's most complex and sophisticated structures.
Molecular & Computational biology
May 4, 2020
0
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