A novel drug, named "FerriIridium," can simultaneously help diagnose and treat gastric cancer. The initially weakly active precursor (prodrug), based on an iridium-containing compound, is selectively activated only after ...
Biochemistry
Jan 23, 2020
0
14
Cell-to-cell contacts are necessary for the survival of human cells under protein-damaging conditions and stress. This was one of the conclusions made by a research team working under the leadership of Lea Sistonen, Professor ...
Cell & Microbiology
Jan 16, 2020
0
5
The essential roles that microbes play in deep-sea ecosystems are at risk from the potential environmental impacts of mining, a new paper in Limnology and Oceanography reports. The study reviews what is known about microbes ...
Environment
Jan 14, 2020
1
169
An interdisciplinary team of scientists from KU Leuven, the University of Bremen, the Leibniz Institute of Materials Engineering, and the University of Ioannina has succeeded in killing tumour cells in mice using nano-sized ...
Bio & Medicine
Jan 9, 2020
0
4968
The protein, called syndecan-4, combines with fellow cell membrane proteins, called integrins, to form protruding 'hands' that sense the environment outside the cell.
Biochemistry
Jan 6, 2020
0
27
Scientists from Utrecht University have applied advanced microscopy to visualize the activity of the widely used drug Taxol. Taxol is often used in cancer chemotherapy. A better understanding of the precise action of the ...
Materials Science
Dec 10, 2019
0
154
A novel engineering process can deliver a safe and effective dose of medicine for brain tumors without exposing patients to toxic side effects from traditional chemotherapy.
Bio & Medicine
Dec 2, 2019
0
925
Many of the currently available drugs are not specific enough to effectively cure complex diseases such as cancer, neurodegenerative diseases and diabetes. In addition, drug resistance reduces the effectiveness of existing ...
Biochemistry
Dec 2, 2019
0
9
Glycosylation—the attachment of sugars to proteins—plays a critical role in both cellular function and in the development of therapeutics, like vaccines.
Cell & Microbiology
Nov 27, 2019
0
57
UCI researchers and collaborators have developed a "lab on a chip" platform to facilitate continuous, inexpensive, rapid and personalized drug screening. The technology is capable of evaluating the effectiveness of treatments ...
Biochemistry
Nov 22, 2019
0
15
