Looking beyond genes to explain blood cells' fates

Scientists often talk about cell fate and commitment in terms of mechanisms that control gene expression (transcription factors, chromatin remodeling, etc.). But by studying Diamond-Blackfan anemia (DBA), rare genetic blood ...

Mice help find gene for bad breath

An international team of researchers has identified a cause for chronic bad breath (halitosis), with the help of gene knockout mice from the UC Davis Mouse Biology Program. The results are published Dec. 18 in the journal ...

Sugar-coated world

Glycans are essential to virtually every biological process in the body. These complex structures—composed of interlocking sugar molecules—adorn the surfaces of cells in fuzzy profusion. Glycans are a crucial part of ...

Nanodiscs catch misfolding proteins red-handed

When proteins misfold, accumulate and clump around insulin-producing cells in the pancreas, they kill cells. Now, researchers, including University of Michigan biophysicists, have obtained a structural snapshot of these proteins ...

Researchers identify defense mechanism of malaria parasite

Portuguese researchers at Instituto de Medicina Molecular (iMM) Lisboa have identified a defense mechanism by which the Plasmodium parasite can survive inside its host's liver cells, a crucial stage in which it acquires the ...

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