Malaria-causing parasite manipulates liver cells to survive
When the malaria-causing Plasmodium parasite first slips into the human bloodstream, injected by the bite of an infected mosquito, it does not immediately target red blood cells.
When the malaria-causing Plasmodium parasite first slips into the human bloodstream, injected by the bite of an infected mosquito, it does not immediately target red blood cells.
Cell & Microbiology
May 22, 2018
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112
Scientists often talk about cell fate and commitment in terms of mechanisms that control gene expression (transcription factors, chromatin remodeling, etc.). But by studying Diamond-Blackfan anemia (DBA), rare genetic blood ...
Cell & Microbiology
Mar 19, 2018
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22
Scientists at The Scripps Research Institute (TSRI) have solved the mystery of the structure of Piezo1, a member of a family of proteins that convert physical stimuli such as touch or blood flow into chemical signals. The ...
Cell & Microbiology
Dec 21, 2017
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343
An international team of researchers has identified a cause for chronic bad breath (halitosis), with the help of gene knockout mice from the UC Davis Mouse Biology Program. The results are published Dec. 18 in the journal ...
Biotechnology
Dec 19, 2017
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91
Glycans are essential to virtually every biological process in the body. These complex structures—composed of interlocking sugar molecules—adorn the surfaces of cells in fuzzy profusion. Glycans are a crucial part of ...
Biochemistry
Dec 18, 2017
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37
A team led by scientists at Van Andel Research Institute (VARI) has revealed for the first time the atomic-level structure of a promising drug target for conditions such as stroke and traumatic brain injury.
Biochemistry
Dec 6, 2017
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155
When proteins misfold, accumulate and clump around insulin-producing cells in the pancreas, they kill cells. Now, researchers, including University of Michigan biophysicists, have obtained a structural snapshot of these proteins ...
Bio & Medicine
Dec 6, 2017
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66
In our bodies, proteins carry out almost all essential processes, and protein malfunction causes many diseases. To study the function of a protein, researchers remove it from the cell and subsequently analyze the consequences. ...
Cell & Microbiology
Nov 16, 2017
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66
Portuguese researchers at Instituto de Medicina Molecular (iMM) Lisboa have identified a defense mechanism by which the Plasmodium parasite can survive inside its host's liver cells, a crucial stage in which it acquires the ...
Cell & Microbiology
Nov 7, 2017
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77
A research project that began 20 years ago with an interest in how lithium treats mood disorders has yielded insights into the progression of blood cancers such as leukemia. The research, which centers on a protein called ...
Biochemistry
Oct 31, 2017
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25