Nothing lives forever, but compared to other cells in the body, hematopoietic stem cells (HSCs) are remarkably long-lived. HSCs are blood-forming cells—they give rise to rapidly dividing progenitor cells, which in turn ...
Cell & Microbiology
11 hours ago
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31
Engineered protein filaments originally produced by bacteria have been modified by scientists to conduct electricity. In a study published recently in the journal Small, researchers revealed that protein nanowires—which ...
Bio & Medicine
Apr 29, 2024
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2
Nicotinamide adenine dinucleotide phosphate oxidase 4 (NADPH oxidase 4, NOX4) is an important member of the NADPH oxidase family that is primarily responsible for the production of H2O2. The regulation of NOX4 activity is ...
Molecular & Computational biology
Mar 27, 2024
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1
Hitting targets embedded within the cell membrane has long been difficult for drug developers due to the membrane's challenging biochemical properties. Now, Scripps Research chemists have demonstrated new custom-designed ...
Biochemistry
Mar 13, 2024
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11
The metabolic process of bilirubin has been a focus of medical research since the abnormal accumulation of bilirubin has been found to be associated with a variety of diseases. Bilirubin is a substance produced by the breakdown ...
Cell & Microbiology
Feb 29, 2024
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22
Neurodegenerative disorders such as Alzheimer's disease affect more than 270 million people worldwide. AD is the leading cause of dementia, resulting in memory loss due to atrophy of neurons in the hippocampus, which is the ...
Bio & Medicine
Jan 4, 2024
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94
Brazilian snake and spider venoms continue to be a source of new discoveries with biotechnological potential. Two recently published studies show how this is possible even in relatively well-studied species such as the lancehead ...
Biotechnology
Jan 4, 2024
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285
Scientists have identified the protein that helps poison dart frogs safely accumulate their namesake toxins, according to a study published today in eLife. The findings solve a long-standing scientific mystery and may suggest ...
Ecology
Dec 19, 2023
1
159
Today, medicines based on antibodies—proteins that fight infection and disease—are prescribed for everything from cancer to COVID-19 to high cholesterol. The antibody drugs are supplied by genetically-engineered cells ...
Biotechnology
Dec 12, 2023
0
74
A team of chemists, microbiologists and physicists at the University of Cambridge in the U.K. has developed a way to use solid-state nanopores and multiplexed DNA barcoding to identify misfolded proteins such as those involved ...
