Related topics: protein · immune system · hiv

Detailed map shows how viruses infect humans

Biologists at Columbia University Vagelos College of Physicians and Surgeons have leveraged a computational method to map protein-protein interactions between all known human-infecting viruses and the cells they infect. The ...

How host-cell enzymes combat the coronavirus

Host-cell enzymes called PARP12 and PARP14 are important for inhibiting mutant forms of a coronavirus, according to a study published May 16 in the open-access journal PLOS Pathogens by Stanley Perlman of the University of ...

New progress in developing an animal model of hepatitis C

Small differences in a liver cell protein have significant impacts on hepatitis C virus replication in mice and humans, findings that could facilitate the development of a mouse model of the infection. The report, led by ...

Topical antibiotic triggers unexpected antiviral response

A Yale-led research team made a startling discovery while investigating the effect of bacteria on viral infections. When they applied a common topical antibiotic to mice before or shortly after infection with herpes and other ...

Mutating Ebola's key protein may stop replication

Researchers may be able to stop the replication of Ebola virus by mutating its most important protein, according to a paper published in the Journal of Biological Chemistry.

Hijacking the double helix for replication

For years, scientists have puzzled over what prompts the intertwined double-helix DNA to open its two strands and then start replication. Knowing this could be the key to understanding how organisms - from healthy cells to ...

New antiviral drugs could come from DNA 'scrunching'

Evidence of DNA "scrunching" may one day lead to a new class of drugs against viruses, according to a research team from the Perelman School of Medicine at the University of Pennsylvania, the Georgia Institute of Technology, ...

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Viral replication

Viral replication is the term used by virologists to describe the formation of biological viruses during the infection process in the target host cells. Viruses must first get into the cell before viral replication can occur. From the perspective of the virus, the purpose of viral replication is to allow production and survival of its kind. By generating abundant copies of its genome and packaging these copies into viruses, the virus is able to continue infecting new hosts. Replication between viruses is greatly varied and depends on the type of genes involved.

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