Expanding DNA's alphabet lets cells produce novel proteins

Scientists are expanding the genetic code of life, using man-made DNA to create a semi-synthetic strain of bacteria—and new research shows those altered microbes actually worked to produce proteins unlike those found in ...

'Semi-synthetic' bacteria churn out unnatural proteins

Synthetic biologists seek to create new life with forms and functions not seen in nature. Although scientists are a long way from making a completely artificial life form, they have made semi-synthetic organisms that have ...

Designer enzyme uses unnatural amino acid for catalysis

University of Groningen chemists have created a new enzyme with an unnatural amino acid as its active centre. They made the enzyme by modifying an antibiotic binding protein which normally acts as a bacterial transcription ...

Team discovers a better way to make unnatural amino acids

Chemists at The Scripps Research Institute (TSRI) have devised a greatly improved technique for making amino acids not found in nature. These "unnatural" amino acids traditionally have been very difficult to synthesize, but ...

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