Related topics: genes · cells · gene expression · stem cells · dna sequences

New insights into how KLF4 influences gene expression

A team led by researchers at Baylor College of Medicine has discovered a mechanism by which transcription factor KLF4 can help to organize chromatin, thus influencing gene expression.

Better in pairs: Proteins can help one another bind to DNA

Scientists from Tokyo Metropolitan University have uncovered a unique mechanism where two transcription factors stabilize each other's binding to DNA in fission yeast. They found that Atf1 and Rst2 help each other stably ...

Evidence for how a key transcription factor manages access to DNA

CTCF is a transcription factor that has been a research target due to its role in regulating a critical oncogene called MYC. Scientists at St. Jude Children's Research Hospital have found direct evidence that CTCF governs ...

How the malaria parasite defends itself from fever

A gene called PfAP2-HS allows the malaria parasite to defend itself from adverse conditions in the host, including febrile temperatures, according to a new study led by the Barcelona Institute for Global Health (ISGlobal), ...

New machine learning technology explores circadian rhythms

We all have an internal clock but what makes us tick? Scientists at the Earlham Institute and IBM Research have developed new artificial intelligence (AI) and machine learning (ML) technology to understand how gene expression ...

How cells remember inflammation

When a tissue experiences inflammation, its cells remember. Pinning proteins to its genetic material at the height of inflammation, the cells bookmark where they left off in their last tussle. Next exposure, inflammatory ...

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