A team of researchers working at the University of Münster has found a high frequency of unwanted duplications during routine CRISPR-Cas9 genetic insertions in mice. In their paper published in the journal Science Advances, ...
Streptomyces bacteria are our primary source of antibiotics, which are produced in the transition from vegetative growth to sporulation in a complex developmental life cycle.
Cell & Microbiology
Dec 03, 2019
0
4
It is the the dream of every molecular geneticist: an easy-to-use program that compares datasets from different cellular conditions, identifies enhancer regions and then assigns them to their target genes. A research team ...
Biotechnology
Nov 27, 2019
0
45
A team from the Broad Institute of MIT and Harvard has developed a new CRISPR genome-editing approach by combining two of the most important proteins in molecular biology—CRISPR-Cas9 and a reverse transcriptase—into a ...
Biotechnology
Oct 21, 2019
2
339
Biomedical engineers at Duke University have used a previously unexplored CRISPR technology to accurately regulate and edit genomes in human cells.
Biotechnology
Sep 23, 2019
0
695
Researchers have engineered a plasmid to remove an antibiotic resistance gene from the Enterococcus faecalis bacterium, an accomplishment that could lead to new methods for combating antibiotic resistance. The research is ...
Molecular & Computational biology
Sep 16, 2019
0
24
Molecular biologists have long thought that domains in the genome's 3-D organization control how genes are expressed. After studying highly rearranged chromosomes in fruit flies, EMBL researchers now reveal that while this ...
Cell & Microbiology
Jul 15, 2019
0
124
By silencing genes, researchers have managed to increase protein production in yeast significantly. This method can lay the grounds for engineering better yeast production hosts for industries producing biopharmaceutical ...
Biotechnology
Apr 29, 2019
0
13
Lifestyle transition is a fundamental mechanism that fungi have evolved to survive and proliferate in different environments. As a typical nematode-trapping fungus, Arthrobotrys oligospora switches from saprophytes to predators ...
Biotechnology
Apr 19, 2019
0
9
A team of biologists and computer scientists has mapped out a network of interactions for how plant genes coordinate their response to nitrogen, a crucial nutrient and the main component of fertilizer. The work, published ...
Biotechnology
Apr 05, 2019
0
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