Researchers reprogram T cells to improve cancer immunotherapy

St. Jude Children's Research Hospital scientists have identified a new therapeutic strategy that enhanced cancer immunotherapy, slowed tumor growth and extended the lives of mice with cancer. The research appears today in ...

'Relaxed' T cells critical to immune response

Like finding that needle in the haystack every time, your T cells manage what seems like an improbable task: Quickly finding a few invaders among the many imposters in your body to trigger its immune response.

Lampreys provide hints to ancient immune cells

Studying lampreys allows biologists to envision the evolutionary past, because they represent an early offshoot of the evolutionary tree, before sharks and fish.

Study reveals dynamics of crucial immune system proteins

Of the many marvels of the human immune system, the processing of antigens by the class I proteins of the major histocompatability complex (MHC-I) is among the most mind-boggling. Exactly how these proteins carry out their ...

'Nanovaccine' reverses type 1 diabetes in mice

A new study, published online April 8 by Cell Press in the journal Immunity, describes a unique therapeutic "nanovaccine" that successfully reverses diabetes in a mouse model of the disease. In addition to providing new insight ...

Decoding the language of immune responses

Fever, cough, sore throat—symptoms in the spotlight in the era of COVID-19—are just some of the telltale signs of our body's immune system kicking into action against an unwanted intruder. Whether triggered by an infection, ...

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