How cells remember inflammation

When a tissue experiences inflammation, its cells remember. Pinning proteins to its genetic material at the height of inflammation, the cells bookmark where they left off in their last tussle. Next exposure, inflammatory ...

Basement membrane underpins tissue interactions in the skin

In a discovery that could pave the way for therapies that promote wound healing and alleviate skin diseases, RIKEN researchers have found that the network of molecules under the outermost layer of mouse skin, the skin epithelium, ...

AI spots healthy stem cells quickly and accurately

Stem cell therapy is at the cutting edge of regenerative medicine, but until now researchers and clinicians have had to painstakingly evaluate stem cell quality by looking at each cell individually under a microscope. Now, ...

Understanding the skin's defense system

It can be easy to forget that the human skin is an organ. It's also the largest one and it's exposed, charged with keeping our inner biology safe from the perils of the outside world.

Researchers create "Ancestry.com" for cells

One of great mysteries of human biology is how a single cell can give rise to the 37 trillion cells contained in the average body, each with its own specialized role. Researchers at Yale University and the Mayo Clinic have ...

Scientists create model of an early human embryo from skin cells

In a discovery that will revolutionize research into the causes of early miscarriage, infertility and the study of early human development—an international team of scientists led by Monash University in Melbourne, Australia ...

Simulations open a new way to reverse cell aging

Research findings by a KAIST team provide insight into the complex mechanism of cellular senescence and present a potential therapeutic strategy for reducing age-related diseases associated with the accumulation of senescent ...

How epithelial cells ward off viruses

A team led by LMU's Veit Hornung has shown that a protein found in skin cells recognizes a specific nucleic acid intermediate that is formed during virus replication. This recognition process subsequently induces a potent ...

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