Researchers from the University of Edinburgh, Scotland, and the University of Cantabria, Spain, have teamed up to develop an AI trained to discover senolytic medicinal chemistry in familiar compounds.
Getting old seems completely avoidable in youth but becomes less and less so as we age. Many of the obstacles of advanced aging are well understood, including declining eyesight, hearing loss, back, neck and arthritic joint ...
Aging and age-related disorders pose a complex challenge to the biomedical research community. To better understand how senescence is regulated is of high significance to promote healthy aging and treat age-associated disorders. ...
Cell & Microbiology
Jul 18, 2022
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86
Cellular senescence—when a cell can no longer divide—is a programmed stage in a cell's life cycle. Sometimes, as in aging, we wish it didn't happen so much and sometimes, as in cancer, we wish it would happen more. Given ...
Cell & Microbiology
Feb 5, 2016
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841
A team led by UT Southwestern Medical Center researchers has discovered a new way that cells regulate senescence, an irreversible end to cell division. The findings, published in Cell, could one day lead to new interventions ...
Cell & Microbiology
Jul 17, 2024
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64
Our cells are surrounded by a fragile membrane that's only 5 nanometers thick, 1/20 of a soap bubble. Cells are easily damaged by physiological activities, including muscle contraction and tissue injury. To cope with such ...
Cell & Microbiology
Feb 22, 2024
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90
A study at the University of Cologne's CECAD Cluster of Excellence in Aging Research has identified a protein complex that is activated by defects in the spliceosome, the molecular scissors that process genetic information. ...
Cell & Microbiology
Feb 2, 2024
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102
Similar to the way expanding companies increase their work forces, cells must boost their production of internal biomolecules when they grow in size in order to stay healthy. In the 1970s, biologists showed that this scaled-up ...
Cell & Microbiology
Jan 29, 2024
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20
Just as healthy organs are vital to our well-being, healthy organelles are vital to the proper functioning of the cell. These subcellular structures carry out specific jobs within the cell; for example, mitochondria power ...
Cell & Microbiology
Jan 1, 2024
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121
The mystery of aging has fascinated people for millennia, with many willing to do anything to halt or reverse this process, because aging is typically associated with gradual deterioration of most body functions. While senescence ...
Evolution
Dec 11, 2023
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