Chromosomes reconfigure as cell division ends

Cellular senescence—when a cell can no longer divide—is a programmed stage in a cell's life cycle. Sometimes, as in aging, we wish it didn't happen so much and sometimes, as in cancer, we wish it would happen more. Given ...

Scientists report inhibition of cellular aging

Aging is the deterioration of a cell's ability to divide and grow as it gets older. This causes degradation of the body and age-related diseases. Prevention of aging is an instinctive desire of humans; thus, it is a task ...

Despite debate, even the world's oldest trees are not immortal

The oldest trees on Earth have stood for nearly five millennia, and researchers have long wondered to what extent these ancient organisms undergo senescence, physically deteriorating as they age. A recent paper studying ginkgoes, ...

RNA provides clues to explain longevity of ginkgo trees

A team of researchers affiliated with several institutions in China and one in the U.S. has found that ginkgo biloba trees do not experience senescence. In their paper published in the Proceedings of the National Academy ...

Simulations open a new way to reverse cell aging

Research findings by a KAIST team provide insight into the complex mechanism of cellular senescence and present a potential therapeutic strategy for reducing age-related diseases associated with the accumulation of senescent ...

Aging cells lose their grip on DNA rogues

(Phys.org)—Transposable elements are mobile strands of DNA that insert themselves into chromosomes with mostly harmful consequences. Cells try to keep them locked down, but in a new study, Brown University researchers ...

Aging cells unravel their DNA

Senescent cells, which are metabolically active but no longer capable of dividing, contribute to aging, and senescence is a key mechanism for preventing the spread of cancer cells. A study in The Journal of Cell Biology identifies ...

Scientists boost lifespan of mice by deleting defective cells

The ageing population is one of the greatest challenges facing society. More people are surviving to old age than ever before, but we currently lack the means to keep them healthy and independent. If a treatment existed to ...

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