RNA microchips

Ribonucleic acid (RNA) is, along with DNA and protein, one of the three primary biological macromolecules and was probably the first to arise in early life forms. In the "RNA world" hypothesis, RNA is able to support life ...

Study reveals how enzyme detects ultraviolet light damage

Damage to DNA is a constant threat to cellular life, and so it is constantly monitored and detected by a family of enzymes called RNA polymerases, resulting in subsequent repair to maintain genome integrity. In a paper published ...

RNA strand enables trapping of uracil in the critical state

Researchers led by Regina de Vivie-Riedle, a professor of theoretical chemistry at LMU Munich, have found indications for a base-independent mechanism that can decrease the photostability of the RNA base uracil.

Tiny nanomachine successfully completes test drive

Together with colleagues from the USA, scientists from the University of Bonn and the research institute Caesar in Bonn have used nanostructures to construct a tiny machine that constitutes a rotatory motor and can move in ...

Researchers develop new ligase for biomedical use

Ligases are enzymes that serve critical functions in cells, helping to fuse together broken strands of DNA and RNA. These enzymes are also important bioengineering tools, useful in genetic sequencing, mutation detection and ...

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